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Artigo em Inglês | MEDLINE | ID: mdl-24984609

RESUMO

Studies were conducted to determine the anaesthetic/sedative concentrations and durations that would maximise anaesthetic/sedative residue concentrations in rainbow trout (Oncorhynchus mykiss) skin-on fillet tissue. Rainbow trout (167-404 g) were exposed to 50 mg l(-1) AQUI-S(®) 20E (10% active ingredient, eugenol) in 17°C freshwater for durations up to 1440 min, 100 and 250 mg l(-1) AQUI-S(®) 20E for durations up to 240 min, and 500 and 1000 mg l(-1) AQUI-S(®) 20E for durations up to 90 min. Fish exposed to 100 mg l(-1) AQUI-S(®) 20E for durations of 30, 60, 120 and 240 min had the greatest eugenol concentrations in the fillet tissue, 50, 58, 54 and 62 µg g(-1), respectively. All other exposure concentrations and durations resulted in significantly lower eugenol concentrations, i.e. all < 39 µg g(-1).


Assuntos
Anestésicos/química , Resíduos de Drogas/análise , Eugenol/química , Carne/análise , Anestésicos/farmacocinética , Anestésicos/farmacologia , Animais , Relação Dose-Resposta a Droga , Eugenol/farmacocinética , Eugenol/farmacologia , Músculo Esquelético/química , Músculo Esquelético/metabolismo , Oncorhynchus mykiss/metabolismo , Reprodutibilidade dos Testes , Pele , Solventes/química , Solventes/farmacocinética , Solventes/farmacologia
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